One dollar from every Teen Burger sold across Canada will be donated to the MS Society towards research and patient support. Customers can also purchase $1 paper cutouts, which at the local restaurant, will enter them into a draw for a chance to win a giant, stuffed A&W “Root Bear.” That draw will happen on Friday.Patrons are also encouraged to bring their classic cars with them, as the day will have a retro theme to it.Last year the event raised over $700,000 nationwide.- Advertisement -Canada has one of the highest rates of MS in the world, with between 50,000 to 75,000 estimated to have the disease. MS is a neurological disease that affects the ability of nerve cells in the brain and spinal cord to communicate with each other, resulting in a broad range of symptoms and often progressing to physical and cognitive disability.
Dr Jerry Bergman is a contributing author and scientist for Creation-Evolution Headlines. Read his Author Profile for his previous articles. (Visited 531 times, 1 visits today)FacebookTwitterPinterestSave分享0 by Dr Jerry BergmanAudio Playerhttps://crev.info/wp-content/uploads/2017/06/Bergman-20170603-ReproducibilityCrisis.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Concerns about unreliable findings in biomedical research, such as cancer research, have been well documented. The problem is known as the ‘reproducibility crisis.’ If this is a problem in a field open to observation and visible in the here and now—biomedical research—what about evolution, which is based on events and extinct life forms that are claimed to have existed eons ago?University of Bristol Professor Marcus Munafò writes in Nature in a book review about the crisis,As scientists, we are supposed to be objective and disinterested, careful sifters of evidence. The reality is messier. Our training can give us only so much protection from natural tendencies to see patterns in randomness, respond unconsciously to incentives, and argue forcefully in defence of our own positions, even in the face of mounting contrary evidence. In the competitive crucible of modern science, various perverse incentives conspire to undermine the scientific method, leading to a literature littered with unreliable findings. It’s an alarming statement. The problem is even more serious, though, with evolutionary studies. These are usually based on fragmentary pieces of evidence, like fossils or genes, that evolutionists sometimes manipulate to defend their particular ideas, or at least to try to provide some semblance of plausibility for their pet theories. As Mark Twain aptly stated a century ago, reconstruction of past life is often based on “nine bones and six hundred barrels of plaster.”A wide-ranging critique of modern biomedical research by science journalist Richard Harris documents the fact that, over the past decade the replication of many published research findings has shown their results to be false, or at least questionable.  And since most findings in biomedical science have not been replicated, the actual failures may be far worse than Harris documents. In his book, Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions, Harris calls for a new discipline to address the problem: he calls it ‘meta-science,’ the scientific study of science itself (4/04/17).Among the shocking examples Harris cites, there was a 2012 study by Glenn Begley that found only 11% (6 out of 53) of ‘landmark’ cancer research studies could be confirmed by the biotechnology firm Amgen.  Since then, “numerous studies (most recently in psychology and cancer biology) have confirmed that failure to replicate published findings is the norm.” Munafò continues, saying that “Harris identifies potential culprits, from the complexity of modern biomedical science to the limitations of tools and training, and perverse incentives in modern academia.”  The worst failure rate came from a study that “replicated 100 psychology studies, and fewer than half got the same results” as the original published papers. The reasons for irreproducibility are many, but whatever the causes, these alarming statistics show that many original or even replicated studies are unreliable. This study was originally published in one of the most prestigious science magazines, Science.  And much research on evolution theories cannot even be replicated in the same way that biomedical research can. At best, the evidence used to arrive at evolutionary conclusions can be reexamined – that is, if permission is granted by the person or organization that owns the artifacts, often bones.Replication is an important scientific tool for exposing fraudulent research. Many consider it a hallmark of science. In actual practice, though, replication often is not carried out for many reasons. Most researchers lack the time, money, and motivation to replicate the work of others because replication is not original science. It is mostly arduous work with few potential rewards. The scientific establishment and the media reward originality. Being second usually wins few accolades. For these and other reasons, replications of most studies are infrequently attempted unless they are particularly controversial.Another reason replication is not often attempted is because it requires the original experimenters to delineate the exact protocol they used for their experiments. But in evolutionary studies, analysis of fossils or other data cited in papers, often are not, or cannot, be perfectly described in detail. The descriptions published by researchers may be detailed, but are often incomplete.Munafò lists a few of the many problems with both biomedical and evolutionary studies:Failure is a normal part of science, but dressing it up as success (for example, by presenting a secondary outcome as the primary outcome) is misleading. So is packaging exploratory, hypothesis-generating work as confirmatory, hypothesis-testing work. Unfortunately, with few ways to publish negative results, such practices are encouraged by incentives to present clean results with a compelling narrative, and be the first to do so.The lesson is clear. We must read all science studies with a skeptical eye – especially studies purported to show evidence for Darwinism. Marcus Munafò, “Reproducibility blues.” Nature, 543:619. March 30, 2017. Richard Harris, Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions. New York: Basic Books, 2017. C. Glen Begley and Lee M. Ellis, “Drug development: Raise standards for preclinical cancer research.” Nature. 483:531–533, 2012. Munafò, Ibid. Brian Handwerk, “Scientists Replicated 100 Psychology Studies, and Fewer Than Half Got the Same Results.” Smithsonian.com, August 27, 2015. “Estimating the reproducibility of psychological science.” Science, 349(6251):943. August 28, 2015. Munafò, Ibid.
SharePrint RelatedNeue Länder-Souvenirs erscheinen demnächst!November 28, 2016In “Deutsch”Fünf neue LändersouvenirsDecember 4, 2017In “Deutsch”Fünf neue Geocaching Ländersouvenirs für 2018December 10, 2018In “Deutsch” Solltest Du bereits einen Geocache in einem dieser Länder gefunden haben, erhältst Du automatisch das entsprechende Souvenir in Dein Profil. Eine Übersicht der bislang erhältlichen Souvenirs befindet sich hier. Um zu sehen, welche Du bereits erhalten hast, wirf einen Blick in Dein Profil auf Geocaching.com.Welches ist Dein Favorit von allen Souvenirs, die Du bisher gesammelt hast? Sag’s uns auf der Geocaching-Facebook-Seite, und dann zieh los und ergatter Dir diese sechs neuen Souvenirs!Share with your Friends:More Halte Deinen Reisepass bereit!Von heute an kann man sechs neue Ländersouvenirs fürs Geocaching-Profil sammeln. Das sind virtuelle Kunstwerke, die in Deinem Geocaching-Profil angezeigt werden, sobald Du einen Geocache in einer bestimmten Region gefunden hast.Es gibt neue Souvenirs für:– Kroatien– Italien– Belgien– Brasilien– Griechenland– Mexiko
Tags:#IPO#Keith Rabois#Khosla Ventures#LinkedIn#PayPal#ReadWrite Mix#ReadWriteMix#tech stocks#Xoom#yelp A Web Developer’s New Best Friend is the AI Wai… owen thomas Why Tech Companies Need Simpler Terms of Servic… Related Posts Top Reasons to Go With Managed WordPress Hosting ReadWrite recently hosted Keith Rabois, the outspoken startup investor who joined Khosla Ventures from payments company Square earlier this year, at our San Francisco headquarters for ReadWriteMix, an events series featuring free-wheeling discussion with prominent tech figures.We started the conversation with an observation Rabois once made to me—tech companies have created a trillion dollars of value for investors over the past decade, but that value has been incredibly concentrated. The rise in value has come from at most 10-15 companies—the likes of Apple, Google, and Facebook.And while hundreds if not thousands of startups get funded every year, only a dozen or so even stand a chance of joining that pantheon.So the question for Rabois, who has worked at PayPal, LinkedIn, Slide, and Square, and backed startups like Yelp, Airbnb, and Yammer: What’s the trick?It’s The Product—But It’s Not Just The ProductWhen Rabois was at PayPal, he ran strategy and legal affairs—including figuring out how to deal with eBay, Visa, and Mastercard, all of which, he says, were trying to kill the payments startup. His training as an antitrust lawyer helped in figuring out PayPal’s competitive strategy—but PayPal didn’t fight primarily in the courts. It fought by getting eBay’s own users on its side.The advice is generally applicable to startups looking to build a business on a bigger company’s platform, as PayPal did by offering credit-card payments on eBay’s auctions site.An audience member asked if startups should band together to contest a company’s capricious or unfair manipulation of a platform on which they’re building businesses. Rabois said he didn’t think that would work.Instead, you have to fight by perfecting your product.“You have to build a product that real users love—not just use, but love,” said Rabois. “And you’ve got to figure out a way to get it in enough of their hands so they truly can’t live without it. Because then when the platform wants to change things, you have real people that are animated. And if those people are animated, they can go to the media, they can go to their congressmen. That’s what you have to have to protect yourself. Anything you do tactically isn’t going to help you. It’s got to be scaled, and it’s got to be true love…. Focus on that.”The Public RouteRabois is also on the board of two public companies, Yelp and Xoom. Yelp has seen a nice runup in its stock recently, and shares of Xoom, an international money-transfer service, are up from their IPO price even after a 59% first-day pop.That goes against conventional wisdom in Silicon Valley these days—that companies should delay going public as long as possible, and avoid the public markets if possible. (Evernote CEO Phil Libin, for example, has talked about his reluctance to take his company public.)Rabois said there were “two schools of thought”—entrepreneurs who are “deferring” IPOs, and entrepreneurs “who welcome it.”“If you’re building an enduring company, one that will last, say, 50 years, it is almost certain that the way you’re going to do that is by becoming a publicly traded company,” Rabois told me. “If your ambition in life is to transform the world through your product technology, and to continue to do that every generation, year after year, year after year, through different management, through different CEOs, a public company is a very good format to do that.”Rabois also noted that going public gives companies a currency for acquisitions.“It also means something to the public,” he said. “It’s actually a safer place to do business. And I think consumers react that way. I think LinkedIn going public was incredibly successful as a marketing campaign for the company. More people became aware of it and filled out profiles.”Rabois said we should expect to see more IPOs in September and October of this year.That’s just some of the ground we covered in our 45-minute chat. Here’s a highlights clip and a complete video of our talk. 8 Best WordPress Hosting Solutions on the Market
Widespread rain lashed most parts of Odisha for the past 48 hours, creating a favourable condition for farming and bringing down temperature levels.The State, which recorded over 30% deficit rainfall in June, has started receiving good rainfall from July largely due to a well-marked low pressure area that lies over southeast Jharkhand and adjoining areas of Odisha and gangetic West Bengal.Under the influence of the atmospheric system, almost all parts of Odisha received rains. Highest precipitation was recorded at Chandbali where 122.3 mm rainfall was measured. Balangir, Phulbani, Bhubaneswar, Sonepur, Angul, Sambalpur and Cuttack received rainfall above 50 mm during 24 hours ending Tuesday morning.The rains brought cheer to farmers as they are getting ready for the Kharif season.Rainfall deficitAccording to the State Revenue and Disaster Management Department, six districts — Balangir, Nayagarh, Nuapada, Kandhamal, Keonjhar and Sundargarh — had rainfall deficit ranging between 39% and 59%. As many as 18 out of 30 districts had recorded rainfall deficit between 19% and 39%. The Bhubaneswar Meteorological Centre had predicted rainfall in the interior areas, especially over central and western districts, over next 24 hours.“The rainfall is critical for furthering farm operations. It restored soil moisture up to some extent,” said Subhendu Rout, a farmer in Jagatsinghpur district.
Highlights from the news file for Friday, Aug. 4———PM SAYS GOVERNMENT CAN HANDLE ASYLUM SEEKER SURGE: Prime Minister Justin Trudeau says Canada has the resources and the capacity to deal with the sudden spike in asylum seekers that have crossed into Quebec. Trudeau said Friday while at an event in eastern Ontario that the government is making sure the influx of people is being properly dealt with. The number of people seeking asylum in Quebec has tripled in the last two weeks, jumping to 150 a day.———ATLANTIC CANADA OFF THE GRID: Many people in Atlantic Canada had to make do without cellphones for much of Friday as a widespread outage also affected internet, TV, wireless and landline phones. Service was slowly being restored by Friday afternoon. Telus said on its website that a problem with the Bell network was to blame. Some flights were delayed as computer issues affected flights at a number of airports.———CANADA CHALKS UP ANOTHER MONTH OF JOB GROWTH: Canada’s jobless rate fell to its lowest level since the start of the financial crisis nearly nine years ago. The jobless rate for July dipped 0.2 to 6.3 per cent as the number of people looking for work declined. Statistics Canada said the economy produced 10,900 net new jobs for the month.———QUEBEC CITY ANNOUNCES MUSLIM CEMETERY: Quebec City Mayor Regis Lebeaume has announced there will be a cemetery for Muslims in the provincial capital. The city is making a parcel of land available and the cemetery is expected to be ready this fall. Quebec City’s Muslims have been looking for a cemetery for two decades, but made a renewed push after they completed the payment for the city’s main mosque in 2011.———SESSIONS WANTS TO PLUG GOVERNMENT LEAKS: Attorney General Jeff Sessions is pledging to rein in government leaks that he says undermine American security. His announcement Friday of a dramatic increase in the number of investigations into criminal leaks comes a week after President Donald Trump accused him of being “weak” on leakers. The timing raises questions about whether the attorney general is working to quell the anger of the man who appointed him.———BC BRINGS BACK HUMAN RIGHTS COMMISSION: The new NDP government in British Columbia is bringing back the provincial human rights commission. It was scrapped by the previous Liberal government in 2002. B.C. is the only province without a commission and instead relies on a tribunal which receives and hears complaints but is not able to do any proactive work.————CANADA’S FOREST INDUSTRY PANS CARIBOU PROTECTION PLAN: The Forest Products Association of Canada says a federal plan to protect caribou is a risky experiment that will do little to help the animals. The group says it will hurt companies already struggling with U.S. softwood tariffs. The federal plan includes an investment in additional research and requests feedback from any organization or person who has updated science. But the forestry association fears an October deadline for provinces to produce caribou range plans means incomplete science will be used to establish the recovery strategy.———AIR QUALITY REMAINS POOR IN BC: Poor air quality caused by smoke from raging wildfires continues to hang over southern British Columbia. An air quality advisory that has spanned from eastern Vancouver Island to the Elk Valley on the Alberta border has now expanded as far north as Prince George. Smoky conditions are causing poor visibility and creating health risks to people with medical conditions, infants and the elderly.———TORONTO SPEEDS WORK ON SAFE INJECTION SITE: Construction on one of three safe injection sites planned for Toronto is due to begin next week. It’s among the measures the city announced this week in a response to a rash of overdoses last week. Toronto’s medical officer of health, Dr. Eileen de Villa, said work on the first site will start Tuesday, with plans for it to open on an unspecified date in the fall.———NHL POWERHOUSE HITS 30: Pittsburgh Penguins captain Sidney Crosby turns 30 on Monday and he’ll celebrate his birthday by parading the Stanley Cup through the Nova Scotia town where he has been a star since he was five. Crosby will mark his third Stanley Cup win by parading with the cup through Cole Harbour. Locals remember Crosby as a hockey prodigy who hasn’t been changed by fame and fortune.———